cannot setup database

When i run the command python manage.py syncdb i got the follwing error

self.connection = Database.connect(**kwargs)
sqlite3.OperationalError: unable to open database file
Exception exceptions.AttributeError: '_shutdown' in <module 'threading' from 'D:
\Python25\lib\threading.pyc'> ignoredDATABASES = {
'default': {
'ENGINE': 'django.db.backends.sqlite3', # Add
'postgresql_psycopg2', 'postgresql', 'mysql',

MY DB SETUP LOOKS LIKE THIS
'default': {
'ENGINE': 'django.db.backends.sqlite3', # Add
'postgresql_psycopg2', 'postgresql', 'mysql',

'sqlite3' or 'oracle'.
'NAME':
'D:\Python25\Lib\site-packages\django\bin\flyp\sqlite3',
# Or

path to database file if using sqlite3.
'USER': '', # Not used with sqlite3.
'PASSWORD': '', # Not used with sqlite3.
'HOST': '', # Set to empty string for
localhost. Not used with sqlite3.
'PORT': '', # Set to empty string for
default. Not used with sqlite3.
}
}

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